DOI: 10.5005/jp-journals-10063-0085 |
Open Access |
How to cite |
How To Cite
How to cite this article:
Nimoshini G, Ramadoss R, Swarnalakshmi R, Vasanthi V, Kumar AR, Divya B. Hyaline Layer of Hopewell-Smith: A Morphometric and Histochemical Analysis. CODS J Dent 2021; 13 (1):3-5.
Background: Hyaline layer of Hopewell-Smith is a homogenous layer between the most external layer of dentin and the internal layer of acellular cementum. The development and functions of intermediate cementum are always controversial.
Aim: To analyze the morphological and histochemical traits of hyaline layer of Hopewell-Smith.
Materials and methods: Analysis of morphological traits were carried out in ground sections of 30 adult teeth with an age range of 20–50 years by polarized light microscopy. Histochemical traits of hyaline layer of Hopewell-Smith was done by using Periodic Acid Schiff and Alcian blue staining.
Results: Morphological traits such as thickness in different regions of root were found to show significant regional variation. Histochemical staining revealed clear demarcation between the dentin and cementum, hyaline layer proved to be a part of the cemental layer than dentin.
Conclusion: Findings such as regional variation in thickness have a remarkable impact on periodontal regeneration. Further correlates with electron microscopic studies will help newer treatment modalities for periodontal pathologies.
CD 44, E-cadherin, Leukoplakia, Lichen planus, SCC
DOI: 10.5005/jp-journals-10063-0080 |
Open Access |
How to cite |
How To Cite
How to cite this article:
Abdal K, Mostafazadeh S, Ghorbani N. Comparison of E-cadherin and CD44 Markers Expression in Oral Lichen Planus, Oral Leukoplakia and Oral Squamous Cell Carcinoma. CODS J Dent 2021; 13 (1):6-10.
Background: Lichen planus and leukoplakia may change dysplastically over time and are considered as premalignant lesions. CD44 and E-cadherin markers appear to have high potential in the premalignant evaluation of oral leukoplakia and lichen planus lesions. Therefore, the aim of this research was to compare the expression of CD44 and E-cadherin markers in oral leukoplakia and lichen planus and oral squamous cell carcinoma.
Materials and methods: This analytical-descriptive research was conducted on 60 blocks of lichen planus, leukoplakia, and squamous cell carcinoma. The blocks were stained by CD44 and E-cadherin antibodies. The data obtained from this research were evaluated by SPSS 22.
Results: Only 30% of squamous cell carcinoma (SCC) samples expressed CD44 marker, while 40% and 50% of leukoplakia and lichen planus samples expressed CD44 marker. The expression of E- cadherin marker in SCC samples was 40% in the range of staining, while it was 50% and 60%, respectively in leukoplakia and lichen planus. The intensity of staining was estimated to be equally severe in leukoplakia and lichen planus samples, and there was not a significant difference between the staining intensity of CD44 and E-cadherin (p < 0.16). While in SCC, 70% of the cases showed mild to moderate expression intensity, while was statistically significant compared to lichen planus and leukoplakia (p < 0.004).
Conclusion: It seems that the severity of CD44 and E-cadherin incidence can indicate the changes in dysplasia and pre-malignancy of oral lichen planus and leukoplakia associated with oral carcinomas.
Aim and objective: This article aims to emphasize the use of a new classification system with a review of the classification systems devised in the past along with their limitations.
Background: There is a lack of universal acceptance of single classification system for furcation involvement due to certain limitations and drawbacks. So, there is a need for a new approach to address the lacuna in the present classification systems. A thorough literature search was done in Medline/PubMed and Google Scholar to incorporate all the classification systems which have been proposed previously.
Review results: Different classifications have been proposed over different eras, the classification given by Glickman being the most common one. The proposed system is based on the site-specific clinical presentation of the furcation defects and takes into consideration the horizontal and vertical components of furcation as well as its exposure.
Conclusion: The present classification has been underscored which is entirely clinical in nature, avoiding the need for anaesthesia, radiographs and open surgeries. This simple and convenient system will assist the clinical practitioners to record the furcation invasion and aid to visualize the clinical picture of the involved tooth.
Clinical significance: This simple and convenient system will assist the clinical practitioners to record the furcation invasion and aid to visualize the clinical picture of the involved tooth.
The novel coronavirus disease is the ongoing pandemic that is caused by severe acute respiratory syndrome coronavirus or SARS-CoV-2. The disease continues to create havoc globally and has created fears in the mind of individuals regarding its spread and transmission. Transmission among humans occur through close contact with an infected individual who may produce respiratory droplets while coughing and sneezing which can remain in air and/or settle on inanimate objects. Therefore, knowledge about the persistence of the virus on various surfaces helps in alleviating irrational fears and also aids in controlling the spread of infection. In this review, an effort was made to compile the data on the persistence of the human coronaviruses such as SARS-CoV-1, Middle East respiratory syndrome (MERS), and SARS-Cov-2 on various surfaces and the biocidal agents that are effective against them.
Aim and objective: Correction of skeletal class II malocclusion by using myofunctional therapy.
Background: B.R, a 12-year old female, reported with the chief complaint of irregularly placed teeth. Clinical examination and analysis of records showed that she had an Angle\'s Class I molar relationship on a Class II skeletal base with retrognathic mandible and deep mentolabial sulcus. There was reduced vertical proportion. Growth pattern was horizontal.
There was increased overjet with lower central incisors missing. Transposition between 42 and 43 was seen. Oral hygiene status was fair to poor. Lips were incompetent at rest (Fig. 1).
Treatment Objective was positive, the saddle angle was normal and mandibular retrognathism was due to the reduced corpus length. The patient had not attained menarche. The cervical vertebral maturation status showed the acceleration phase of growth CVMI 2 (Cervical Vertebrae Maturity Index) (Fig. 2).
Treatment involved orthodontic fixed appliance mechanotherapy using metal brackets with 0.022 × 0.028 MBT prescription. Optimal orthodontic and esthetic result was achieved by nonextraction treatment protocol.
The paper reports a rare case of mild form of Bushy syndrome with facial abnormalities. Other names for this syndrome are Cornelia de Lange syndrome/Brachmann- de Lange syndrome/Amsterdam dwarfism/Bushy syndrome. Few case reports were reported in the literature and this case report was presented with the motto of fabricating feeding palate in this syndromic patient and the procedure is similar to that of any other cleft palate.