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VOLUME 5 , ISSUE 1 ( March, 2013 ) > List of Articles


Granular Cell Ameloblastoma - A Case Report

Mandana Donoghue, M Selvamani, Rajeshwari G. Annigeri, G.S Madhushankari, A. Yamuna Dev, Rajay A.D. Kamath

Citation Information : Donoghue M, Selvamani M, Annigeri RG, Madhushankari G, Dev AY, Kamath RA. Granular Cell Ameloblastoma - A Case Report. CODS J Dent 2013; 5 (1):1-4.

DOI: 10.5005/cods-5-1-1

License: CC BY-NC-ND 3.0

Published Online: 01-06-2013

Copyright Statement:  Copyright © 2013; The Author(s).


Granular cell ameloblastoma is a rare variant, accounting for 1-5% (3.5%) of ameloblastomas. It has clinical behavior similar to other subtypes, and show high tendency to recur on conservative surgical approaches. It can also show metastasis, hence the treatment plan should include regular follow up of the patients, after radical surgery. Here we are presenting a case report of granular cell ameloblastoma occurring in a 45 years old male patient clinically, the lesion was occurring in the left posterior mandible creating soap bubble appearance on radiography. Histopathologically, granular cell changes were prominent. The granular appearance is due to lysosomal aggregation and their presence indicates degenerative change or related to aging phenomenon rather than aggressiveness. The lesion was treated by surgical resection and a period of 3 years follow up showed no recurrence.

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