CODS Journal of Dentistry

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VOLUME 8 , ISSUE 2 ( 2016 ) > List of Articles

ORIGINAL ARTICLE

Evaluation of Curcumin 10 mg (Curenext®) as Local Drug Delivery Adjunct in the Treatment of Chronic Periodontitis: A Clinical Trial

Shobha Prakash, Priyanka Shivanand, Kangowkar V Vandana, Kharidhi L Vandana

Keywords : Curcumin, Local drug delivery, Periodontitis, Scaling and root planing

Citation Information : Prakash S, Shivanand P, Vandana KV, Vandana KL. Evaluation of Curcumin 10 mg (Curenext®) as Local Drug Delivery Adjunct in the Treatment of Chronic Periodontitis: A Clinical Trial. CODS J Dent 2016; 8 (2):59-63.

DOI: 10.5005/jp-journals-10063-0014

License: CC BY-NC-ND 3.0

Published Online: 00-12-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction: Plaque control combined with scaling and root planing (SRP) is an effective therapeutic modality for arresting periodontitis. Due to limitation of mechanical therapy such as SRP, local application of drugs has been initiated. Turmeric is not just a remedy, it is the “cure.” Materials and methods: A total of 14 patients diagnosed with chronic periodontitis were included in a split mouth study. Using the split study protocol, upper arch received SRP alone (control group) and lower arch received SRP + intrapocket application of curcumin (CU) 10 mg (Curenext®; experimental group) in selected sites. Plaque index (PI), gingival bleeding index (GBI), gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) were assessed at baseline and 21st, 30th, and 90th day. Results: Intragroup analysis and intergroup analysis showed significant reduction (p < 0.000) in clinical analysis from baseline to 90th day with comparatively better outcomes in the SRP + CU group. No adverse effects were reported. Conclusion: Curcumin has a number of medicinal properties; it is beneficial in many ways and acts as a capable adjunct to SRP in the treatment of periodontal disease.


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