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VOLUME 10 , ISSUE 1 ( January-June, 2018 ) > List of Articles

Original Article

Evaluation of Garlic Extract Gel as Local Drug Delivery in the Treatment of Chronic Periodontitis: A Clinical Study

Ravi T Reddy, Vandana KVP Kumar, Shobha Prakash

Keywords : Clinical attachment level, Garlic, Herbal, Local drug delivery, Periodontitis, Probing depth, Scaling and root planing

Citation Information : Reddy RT, Kumar VK, Prakash S. Evaluation of Garlic Extract Gel as Local Drug Delivery in the Treatment of Chronic Periodontitis: A Clinical Study. CODS J Dent 2018; 10 (1):1-6.

DOI: 10.5005/jp-journals-10063-0044

License: CC BY-NC 4.0

Published Online: 01-04-2020

Copyright Statement:  Copyright © 2018; The Author(s).


Objective: Here an attempt is made to assess the clinical benefits of garlic extract gel when used as an adjunct to nonsurgical periodontal therapy. Materials and methods: A total of 13 patients with periodontitis (AAP criteria) were selected. A split mouth design was used and sites in each patient were allocated into the experimental group and the control group. In the experimental group, sites were treated with scaling and root planing (SRP) + garlic gel. In the control group, sites were treated with SRP alone. Plaque index (PI), gingival bleeding index (GBI), gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) were assessed at baseline on 21st day, 30th day, and 90th day. Results: On intragroup comparison, the reduction in clinical parameters like PI, GI, GBI, and PPD was highly significant in both test and control groups (p ≤ 0.001), whereas CAL showed no significant gain in the control group but highly statistical significant result was seen in the test group. On intergroup comparison, all the clinical parameters like PI and CAL showed statistically significant (p ≤ 0.05) improvement the in test group when compared with that of the control group, whereas GI, GBI, and PPD showed statistically high significant (p ≤ 0.001) improvement in subjects with SRP + garlic gel when compared with SRP alone. Conclusion: These results conclude that garlic gel can be a used as an antibacterial and anti-inflammatory agent in adjunct to SRP. However, further research with larger samples needs to be focused to confirm the use of garlic in clinical practice.

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